A shot in the arm for new antibiotics

Document Type

Article

Publication Date

10-2019

ISSN

1546-1696

Publisher

Springer Nature

Language

en-US

Abstract

To the Editor — On 1 October, a new US Centers for Medicare and Medicaid Services (CMS) rule comes into effect that enhances economic incentives for newer antibiotics administered in US hospitals. The rule represents an economically significant post-approval (‘pull’) incentive to boost antibiotic development. If it is followed by further regulatory action in the coming year, it may prove to be the largest antibiotic pull incentive ever created by the US government. Although the new rule is a welcome shot in the arm for antibiotic discovery and development, the current moribund state of the antibacterial R&D ecosystem means that other incentives, such as a ‘market entry reward’, are still needed to fully incentivize drug companies to embrace (rather than leave) this space

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